Data Scientist (Bioinformatics)

May 29, 2024

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About Mitra bio

Mitra bio is a start-up backed by Illumina and the University of Oxford that aims to disrupt skincare and skin health through data. Mitra is developing a skin longevity platform powered by non-invasive sampling and epigenetics to enhance diagnostics and personalized treatments for the skin. 

There will be ample opportunity for growth with share options available.

Role

This is not a typical data science/bioinformatics position. You will be working on cutting edge omics studies to advance skin diagnostics and discovery of novel anti-aging treatments. Your work will translate into an impactful product in the hands of the consumer. In this customer focused and technically savvy role, you will deliver data science solutions for Next Generation Sequencing with a focus on DNA methylation. You will work in a multi-disciplinary team and will have the opportunity to be involved in strategy to develop bespoke methodologies and ML/AI algorithms for diagnostics and prediction tool development.

Responsibilities: 

  • Work as part of a multidisciplinary team;
  • Design and deliver in-depth, and start-of-the-art client reporting on of high throughput data generated from various NGS and array data from various domains (specifically epigenomics, but also including genomics, transcriptomics, etc.);
  • Build and optimize ML models for biological age determination and disease stratification based on epigenetic data;
  • Work with AI models to predict skin phenotypes from epigenetics and comprehensive metadata/clinical endpoints;
  • Work on the AWS infrastructure (data storage, analysis pipelines, compute nodes and AWS specific user/role/resource permissions);
  • Contribute to the expansion of the existing computational infrastructure including but not limited to: expansion of the AWS compute framework with a heavy bias on increasing automation and throughput, designing and developing new bioinformatic analysis pipelines and using cutting edge downstream analysis techniques to produce actionable results;
  • Manage multiple projects simultaneously and complete projects in a timely & reliable manner;
  • Present experimental plans and results to internal and external stakeholders;
  • Be involved in hiring and team growth.

Essential skills and experience

  • MSc or equivalent experience in Bioinformatics, Biochemistry, Computer Science or a related subject;
  • 2+ years’ experience delivering bioinformatics and ML based solutions to the industry; 
  • Strong experience in software development (mainly Python), test-driven development and proficiency in collaborative software development practices (code reviews, branching models);
  • Experience in version control, CI/CD and automated deployment;
  • Experience in cloud computing (e.g. AWS/Azure/GCP);
  • Familiarity in tools used in modern Illumina NGS data analysis;
  • Experience of building pipelines in Nextflow;

Desirable:

  • Experience in analysis of epigenetics data such as DNA methylation and variant analysis (GWAS) is also advantageous;
  • Experience working in agile environments;
  • Experience deploying and maintaining secure computing environments;
  • Familiarity with research governance, The Data Protection Act and Good Clinical Practice;
  • Curiosity on using and implementing current AI technologies into company workflows. 

Apply to Data Scientist (Bioinformatics)

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